b-CYCLODEXTRIN
b- cyclodexrin pharmaceutical industry, cyclodextrins have mainly been used as complexing agents to increase the aqueous solubility of active substances poorly soluble in water, in order to increase their bioavailability and to improve stability.
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β-Cyclodextrin (β-CD) is a cone-shaped molecule. It is hydrophilic at the outer surface of the cavity for many hydroxyl groups, but hydrophobic in the cavity.
β-Cyclodextrin is used as a complexing agent in drug delivery because it forms an inclusion complex with a drug molecule.
b-CYCLODEXTRIN Increasing the dose to either 4000 mg/kg weekly or every other day delayed clinical disease onset, increased survival time, corrected cholesterol.
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